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What is Depakote (divalproex sodium) ER?

Depakote ER is a brand name for the active ingredient divalproex sodium in an extended-release dosage form. It is used to treat people with epilepsy, and sometimes people with migraines or the manic episodes of bipolar disorder. Depakote ER increases the chemical gamma-aminobutyric acid (GABA) in the brain. GABA helps to regulate brain signals, especially abnormal ones that cause seizures.

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