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What should I tell my pharmacist before taking Depakote?

If you or any of your blood relatives has a condition called urea cycle disorder (which interferes with the ability to turn food into energy), tell your doctor or pharmacist before taking this drug. You may not be able to take Depakote. Discuss all other major health problems or diseases you have had and any medications, vitamins, dietary supplements, or medicinal herbs that you take. If you take any of the following drugs you will likely still be able to take Depakote, but your doctor may want to adjust your dose: acyclovir (Zovirax); antidepressants, especially tricyclics such as amitriptyline and nortriptyline (Pamelor); blood-thinning medications such as warfarin (Coumadin); aspirin; clonazepam (Klonopin); diazepam (Valium); any medications for treating anxiety or any form of mental illness; other medications for preventing seizures, such as carbamazepine (Tegretol), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), mephobarbital (Mebaral), phenobarbital, phenytoin (Dilantin), primidone (Mysoline), and topiramate (Topamax); meropenem (Merrem IV); rifampin (Rifadin); sedatives; sleeping pills and tranquilizers; tolbutamide; and zidovudine (Retrovir).

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.