What are the side effects of rufinamide?

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There are several side effects of rufinamide. The most common side effects include headache, sleepiness, difficulty walking, loss of coordination, uncontrollable movements of the eyes, uncontrollable movement or activity, difficulty paying attention, uncontrollable shaking of a part of the body, dizziness, loss of appetite, vomiting, nausea, stomach pain, and back pain.

Alert your doctor immediately if you have any serious side effects. More severe side effects include rash, hives, fever, itching, swelling of the face (indicators of an allergic reaction), new seizures, urine changes, decreased coordination, persistent dizziness or weakness, sore throat, odd mood or mental state changes, sleepiness, insomnia, decreased ability to respond to others, yellowing of the skin or eyes, blurred or double vision, light-colored stool, and dark-colored urine.

There is also an increased risk of suicidal thoughts and behavior when taking rufinamide. Medications such as carbamazepine, primidone, triazolam, valproate or valproic acid, interact with rufinamide and can result in serious health problems. 

Talk to your doctor about all of your health concerns and about all prescription and over-the-counter drugs, vitamins, and herbs that you are using, before taking rufinamide.