How should I take divalproex sodium ER?

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Divalproex sodium ER is an extended-release medicine and should be taken once a day. The medication can be taken with or without food. Since this medication is extended-release, you should not crush it, break it, or chew it. Divalproex sodium ER should be taken at the same time everyday. You should not stop taking divalproex sodium ER until you speak with your doctor. It should be kept out of the reach of children and stored at room temperature.