Does Phenytek interact with other medications or foods?

Phenytek (phenytoin) interacts with alcohol. While taking Phenytek, avoid taking antacids that contain calcium, such as Maalox, Mylanta, and Tums. If you must use these products, do not take them at the same time as you take Phenytek. Discuss how long to wait before taking the antacid with your doctor. Phenytek may also interact badly with many other medications, including antidepressants and other drugs for seizures. Be sure to tell your doctor if you take any of these drugs or supplements: heart rhythm drugs such as amiodarone; blood thinners such as warfarin; some antidepressants, including amoxapine or clomipramine, amitriptyline, desipramine, maprotiline, or nortriptyline, doxepin, trimipramine, imipramine and protriptyline; chloramphenicol and chlordiazepoxide; diazepam; digoxin; disulfiram; and doxycycline drugs; fluoxetine; furosemide; stomach acid drugs such as cimetidine, famotidine, nizatidine, and ranitidine; birth control pills, patches, rings, or injections; hormone replacement therapy (HRT); drugs for mental illness; drugs for nausea; other seizure medications such as carbamazepine, ethosuximide, methsuximide, phenobarbital, and valproic acid, methylphenidate; molindone; oral steroids such as dexamethasone, methylprednisolone, prednisolone, or prednisone; paroxetine; quinidine; reserpine; rifampin; salicylate pain relievers such as aspirin, choline magnesium trisalicylate, choline salicylate, iflunisal, magnesium salicylate, and salsalate; sucralfate; sulfa antibiotics; theophylline; ticlopidine; tolbutamide; trazodone; and vitamin D.  If you must take some drugs or supplements, you may be able to continue with them while taking Phenytek, but your doctor will want to monitor you closely for side effects and interactions. For some drugs, you may need to change the dose.

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