Valproic acid and topiramate have been considered the top choices among anticonvulsants for reducing migraine frequency. Valproic acid reduces the number of migraines by about 4 per month. Topiramate reduces migraines by about 1 per month. More research is needed to know for sure if carbamazepine or gabapentin is effective. Most other anticonvulsants have not been found to reduce migraine frequency.
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