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How effective are anticonvulsants for treating migraines?

Donna Hill Howes, RN
Family Practitioner

Valproic acid and topiramate have been considered the top choices among anticonvulsants for reducing migraine frequency. Valproic acid reduces the number of migraines by about 4 per month. Topiramate reduces migraines by about 1 per month. More research is needed to know for sure if carbamazepine or gabapentin is effective. Most other anticonvulsants have not been found to reduce migraine frequency. 

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