How does Depakote treat seizures?

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Depakote is known as an anticonvulsant medication, which can be used to treat seizures caused by a variety of factors, including epilepsy. Depakote can be used by itself or combined with other medications to protect against different types of seizures, including complex partial seizures and simple or complex absence seizures. Depakote works by increasing the amount of gamma-aminobutyric acid (GABA) in the brain. GABA is a natural chemical that stops or slows down other brain signals. Increasing GABA helps prevent the abnormal brain signals that lead to a seizure. It is also thought that Depakote may prevent seizures by affecting sodium channels in the brain. Depakote is approved to treat seizures in people who are over 10 years of age.