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How is gabapentin used to treat hot flashes?

Donna Hill Howes, RN
Family Practitioner

Gabapentin (Neurontin, Gralise) was developed to treat seizures. It has also been used to help to reduce hot flashes, though it is not approved for this use by the FDA. Gabapentin, especially in doses of 900 mg a day, can reduce both the frequency and severity of hot flashes by about 50%. These effects apply not only to women going through natural menopause, but also to those with early menopause brought on by cancer chemotherapy.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.