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What is Praxbind?

Praxbind (idarucizumab) is a medication used to reverse the effects of another medication, Pradaxa (dabigatran). Pradaxa is a blood thinner (anticoagulant) used to prevent blood clots, but in cases where it leads to uncontrolled bleeding, or if its effects need to be stopped so that emergency surgery or other procedures need to be performed, Praxbind is used. Praxbind may be injected or infused with an IV. Anticoagulant therapy can usually be resumed after the situation that required Praxbind is resolved. Possible side effects to Praxbind include allergic reaction, headache, constipation, and delirium. Patients with hereditary fructose intolerance have had dangerous reactions to Praxbind, which contains sorbitol. 

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