What drugs may interact with anticoagulants?

Donna Hill Howes, RN
Family Practitioner

The following drugs may interact with anticoagulant drugs, leading to side effects:

  • antiplatelet agents (may interact with apixaban and rivaroxaban)
  • aspirin (may interact with dabigatran)
  • conivaptan (may interact with apixaban and rivaroxaban)
  • CYP3A4 inducer (may interact with apixaban and rivaroxaban)
  • deferasirox
  • deoxycholic acidcurrent medication: enzalutamide (174) [48541]
  • enzalutamide (may interact with warfarin)
  • ibritumomab (may interact with dabigatran and warfarin)
  • ibrutinib (may interact with warfarin)
  • idelalisib (may interact with apixaban and rivaroxaban)
  • milnacipran (may interact with warfarin)
  • naproxen (may interact with apixaban and rivaroxaban)
  • nonsteroidal anti-inflammatory drugs (may interact with dabigatran)
  • obinutuzumab
  • omacetaxine
  • regorafenib (may interact with warfarin)
  • tositumomab (may interact with dabigatran)
  • venlafaxine (may interact with warfarin)
  • vorpaxar (may interact with apixaban, rivaroxaban, dabigatran, and warfarin)

If you take warfarin, you should avoid ginkgo biloba and green tea. If you take apixaban or rivaroxaban, you should avoid St. John's wort. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.