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Should someone on Coumadin take aspirin during a heart attack?

Linda Martinez
Cardiac Rehabilitation

Yes. Aspirin and warfarin (Coumadin) work in different ways on the clotting cascade. Warfarin makes the blood take longer to clot, but the blood will still clot. When someone is having a heart attack, it means they are most likely clotting off an artery that supplies the heart muscle with blood. Aspirin directly affects the platelets ability to "clump" and cause a clot. Aspirin should still be given if a person on warfarin is suspected of having a heart attack.