What are the side effects of clindamycin phosphate?

Stacy Wiegman, PharmD

Pharmacy

Common side effects of the topical formulations include skin problems, such as irritation, dryness, peeling, burning, itching, redness, pimples and excess oil. These generally do not require a doctor's visit unless they become severe. More serious side effects include: stomach cramping, diarrhea, changes in bowel movements, antibiotic-associated colitis. These happen more often with the intravenously administered clindamycin phosphate. Serious allergic reaction, such as labored breathing, chest pain or facial swelling may occur with any of the formulations. If you are taking clindamycin phosphate and experience these or other worrisome side effects, you should see a doctor as soon as possible.

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