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What is demeclocycline (Declomycin)?

Demeclocycline (Declomycin) is a prescription antibiotic used to treat pneumonia, acne, Lyme disease and other infections. It is in the drug class of tetracycline antibiotics. Like other tetracyclines, demeclocycline should be taken on an empty stomach, and should never be taken with dairy products like milk, yogurt, cheese or ice cream.

Demeclocycline is also often used for SIADH, although it is not approved by the FDA for this. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disorder in which too much natural antidiuretic hormone is secreted and urination is inhibited. Demeclomycin causes increased urination in these people.

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