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What conditions is quinupristin-dalfopristin used to treat?

In adults, quinupristin-dalfopristin (brand name Synercid) is approved by the US Food and Drug Administration (FDA) to treat complicated skin infections caused by the organisms methicillin-susceptible Staphylococcus aureus, a form of the bacteria Staphylococcus aureus (often shortened to “Staph aureus”) that can be stopped by the antibiotic methicillin, and Streptococcus pyogenes, another type of bacteria that can cause serious skin infections. Besides this use, Synercid has been used to treat life-threatening infections caused by another bacteria called Enterococcus faecium, including those resistant to vancomycin. However, the FDA recently removed its approval for this use of Synercid. Currently, it is FDA-approved to treat only skin infections caused by Staph aureus and Streptococcus pyogenes. Quinupristin-dalfopristin may also be used in children 16 years old or older.

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