How does Macrodantin interact with other medications or food?

Antacids, particularly those that contain magnesium trisilicate, may decrease the absorption of the nitrofurantoin and thus decrease the bacteria-killing effects of Macrodantin. Uricosuric drugs, such as  probenecid and sulfinpyrazone, can reduce the elimination of Macrodantin and increase the risk of side effects.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.