What should I know about tobramycin injection before receiving it?

You should discuss the use of tobramycin with your doctor if you are pregnant, thinking of becoming pregnant or nursing. Tell your doctor if you have myasthenia gravis or Parkinson's disease. You should not receive this medication if you are allergic to it or any sulfite medications. Any nerve trouble, kidney problems, hearing difficulties, severe burns or dehydration should be discussed with your doctor before starting tobramycin. When self-administering tobramycin, be sure never to use it if there are particles in the solution, if the solution is cloudy or discolored or the vial has been damaged. Never reuse syringes and make sure to dispose of them properly. Missed doses should be administered as soon as possible, and you should ask your healthcare provider how to reschedule the remaining doses. You should drink extra fluids when you are receiving tobramycin. Diarrhea is a common side effect when using any antibiotic; however, you may experience severe diarrhea known as pseudomembranous colitis. If you have cramps, severe diarrhea and bloody stools, contact your doctor immediately. If you are an older adult, your dosage might be reduced.

Children under 10 years of age should not be given tobramycin, as the effects are not well known at this time. You should discuss any medications or food allergies with your doctor before using tobramycin. If you are using diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), cyclosporine or methoxyflurane, you should not receive injections of tobramycin. Cephaloridine, cephalosporins (e.g. ceftizoxime), cisplatin, colistin, fludarabine, nitrosoureas (eg., carmustine), polymyxin B, vancomycin or viomycin may increase the risk of side effects associated with tobramycin, including increased risk of kidney damage or hearing loss. Beta-lactam antibiotics (e.g., penicillin, imipenem, ceftizoxime) may decrease tobramycin's effectiveness. Nondepolarizing muscle relaxants (e.g., atracurium) or succinylcholine should not be taken with tobramycin, because it may increase their side effects.  

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.