Does Singulair interact with other medications or food?

Singulair can potentially interact with other medications. Some of the medicines that may lead to Singulair drug interactions include: Certain anticonvulsants (seizure medications), including carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR), fosphenytoin (Cerebyx), oxcarbazepine (Trileptal), phenobarbital (Luminal) Pentobarbital (Nembutal), phenytoin (Dilantin, Phenytek), primidone (Mysoline). Singulair may also interact with rifamycin antibiotics, including rifabutin (Mycobutin), rifampin (Rifadin) and rifapentine (Priftin). Singulair (montelukast) can be taken with or without food.