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What are the side effects of isotretinoin?

The most common non-serious side effects of isotretinoin are dry skin, acne flare-ups, skin irritation, joint or back pain, agitation or drowsiness. Also, this medication often causes increased susceptibility to sunburn, which you can avoid by taking precautions when going outside during sunny weather, wearing sunscreen, covering yourself to avoid overexposure and following your doctor's instructions. Isotretinoin often causes dryness in the eyes, making wearing contacts or seeing at night difficult. The more serious side effects of isotretinoin that you should watch for include: changes to your mental state, depression, difficulty sleeping, anxiety or aggressiveness, hallucinations and other behavioral effects. Talk to your doctor if you experience any of these side effects or if you experience sudden numbness, difficulty seeing or pain around your eyes, difficulty hearing or ringing noises, seizures, intense stomach pain or vomiting, increased heart rate, loss of appetite, diarrhea or rectal bleeding, intense nausea, flu symptoms like chills or fever, discolored stools or urine, jaundice, joint or bone pain or excessive bruising or bleeding. Finally, if you experience signs of an allergic reaction to isotretinoin, such as swelling around your face or throat, hives or intense difficulty breathing, immediately seek emergency medical attention.  

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.