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What are the side effects of isoniazid-rifampin?

Mild side effects associated with isoniazid-rifampin include: minor weakness or fatigue and a reddish-orange stain in your urine, stool, saliva, sweat or tears. Other side effects include: heartburn, gas, nausea, minor upset stomach or stomach cramps, diarrhea, headaches, sleeping problems and feeling dizzy or drowsy. Immediate medical help is needed if any of the following side effects occur: diarrhea or nausea that is severe; vomiting; lack of appetite; yellowed eyes or skin; mouth that is sore, red or cracked at the corners; urine that is dark, scant, absent or increased; blood in feces; menstrual changes; feeling exhausted or overly weak; bleeding or bruises that are unusual; headaches; pain in the stomach, bones, muscles or joints; swelling in the joints; tingling or numb feet or hands; sore throat; fever or chills; itching, rash or hives; vision problems; memory problems; feeling confused or irritable; odd behavior; generally feeling unwell; seizures; allergic reaction, such as hives, breathing problems, closing of the throat, chest tightness or swollen face, tongue or lips.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.