What is trimetrexate glucuronate?

Stacy Wiegman, PharmD

Pharmacy

Trimetrexate glucuronate is an antimicrobial drug and is given intravenously. It is used to treat Pneumocystis pneumonia in people with compromised immune systems, and it is usually given if other drugs have not worked. Trimetrexate glucuronate must be administered along with a drug called leucovorin in a hospital setting. The typical length of treatment is three weeks. Trimetrexate glucuronate is the active ingredient in the prescription brand-name drug Neutrexin. Neutrexin is currently not being marketed in the United States.

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