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What are the side effects of atovaquone and proguanil?

Side effects of atovaquone-proguanil may include weakness, loss of appetite, nausea, diarrhea, vomiting, dizziness, difficulty sleeping, itching, cough or headaches. Some side effects are more serious and require you to contact your doctor immediately. These include: severe nausea, vomiting or diarrhea; stomach pain; dark urine; clay-colored stools; jaundice; unusual bleeding or bruising; severe skin rash; mouth sores; fever; weight loss; tiredness; unusual aches or pains; breathing problems; vision changes; and redness, blistering, loosening or peeling on the skin or inside of the mouth. Atovaquone-proguanil also may cause an allergic reaction. Symptoms of this include: hives, rash, difficulty breathing or swelling of the lips, face, tongue and throat. If you experience symptoms of an allergic reaction, seek emergency medical attention.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.