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How does rifabutin treat Mycobacterium avium complex (MAC) disease?

Rifabutin is prescribed to prevent Mycobacterium avium complex (MAC) disease from spreading throughout the body in people with HIV infection. It is an antimycobacterial agent that is thought to interfere with mycobacterial DNA production and, thus, decrease the spread of MAC. It is also frequently used for the treatment of MAC and tuberculosis.

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