What should I know about pyrimethamine before taking it?

You may not be able to take pyrimethamine (Daraprim) if you have megaloblastic anemia, seizures, epilepsy, kidney or liver disease, or a lack of vitamin B in the body. Your doctor may determine that pyrimethamine is not right for you or may have to adjust the dosage.

Seek immediate medical attention by calling 911 if you experience serious side effects of pyrimethamine, including if you experience a rash, sore throat, bruising, tongue swelling, or become pale. Taking this medicine in high doses can cause blood problems.

It is not known whether pyrimethamine is safe to take during pregnancy. Talk to your doctor before starting pyrimethamine if you are pregnant, may become pregnant, or are breastfeeding.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.