What are the risks of taking pyrimethamine?

Pyrimethamine (Daraprim) is not recommended for people with certain conditions. If you have anemia or other blood problems, large doses of pyrimethamine can worsen these illnesses. In addition, high doses of pyrimethamine can create blood problems that can lead to more infections and can slow healing time. Dental work is not recommended during pyrimethamine treatment, and extra care must be taken when brushing teeth, flossing, or using toothpicks.

If you have a vitamin B deficiency caused by alcoholism or a malabsorption disease, pyrimethamine may make your deficiency worse. Epileptics and those with other seizure disorders may be more likely to have a seizure while on pyrimethamine.

Pyrimethamine's use during pregnancy or breastfeeding has not been widely studied. Talk to you doctor about the benefits and the risks of pyrimethamine treatment if you are pregnant, breastfeeding, or may become pregnant.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.