Are there any risks in receiving streptomycin?

As with all antibiotics, there is a risk of secondary infection if streptomycin is used over a long time or frequently. People who have kidney problems may have toxic nerve reactions after receiving streptomycin; make sure your doctor knows about all of your medical conditions before receiving an injection. People who use cyclosporine, cephalosporins, methoxyflurane, vancomycin, nitrosoureas and ibuprofen or similar drugs at the same time as streptomycin also are at risk for kidney toxicity. Other medications, namely fludarabine and indomethacin, may increase streptomycin's intended effects and side effects. The effects of nondepolarizing muscle relaxants, and succinylcholine, may increase while using streptomycin. Severe side effects include: deafness, especially if you have problems with your eighth cranial nerve or use loop diuretics while using streptomycin. Pregnant and breast-feeding women should not use streptomycin because it could seriously harm fetal and child development.