What are the risks in taking isoniazid, pyrazinamide, and rifampin?

Isoniazid-pyrazinamide-rifampin, a combination antimicrobial drug used to treat tuberculosis (TB) infection, carries risks of side effects ranging from vision problems to hepatitis. The combination carries the same risks as each of the components: isoniazid, pyrazinamide and rifampin. Your doctor should monitor you for these problems while you are taking this drug.