What medications can interact with tipranavir?

A number of medications can interact with the HIV drug tipranavir (Aptivus), including the following:

• antidepressants, such as fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft)
• the antipsychotic drugs pimozide (Orap) and quetiapine (Seroquel)
• migraine headache medicines called ergot alkaloids
• calcium channel blockers, such as diltiazem (Cardizem, Dilacor, Tiazac)
• immunosuppressants, such as cyclosporine (Neoral, Sandimmune)
• medications for diabetes, such as glimepiride (Amaryl), glipizide (Glucotrol) and glyburide (Micronase, Diabeta, others)
• other medications for HIV, including abacavir (Ziagen, in Epzicom, in Trizivir)
• statins, which treat high cholesterol, such as atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor)
• antifungal medicines, such as Diflucan and Sporanox
• medicines for high blood pressure and heart conditions
• drugs that fight seizures
• estrogen replacement therapy and oral contraceptives
• drugs that treat erectile dysfunction, such as sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra)

It's important to review all drugs and supplements you take with your doctor. It's helpful to bring all your medications, supplements, vitamins and herbal therapies to your doctor to ask if any may interact with tipranavir.