What can I expect to happen if I stop taking adefovir dipivoxil (Hepsera)?

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When you go off adefovir (Hepsera) your hepatitis may get worse, especially in the first three months. So you will need to have regular blood tests to check your liver function and hepatitis B viral levels. If it looks like your hepatitis is worsening, your doctor may put you back on adefovir. Because of the risks associated with quitting the drug, you should talk to your doctor before stopping the medication.