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What should I know about Kaletra tablets before using them?

Before taking Kaletra, you should know that it can have adverse interactions with many other drugs and combining Kaletra tablets with them can cause potentially fatal side effects. While taking Kaletra, do not take sildenafil, rifampin, triazolam, lovastatin, pimozide, simvastatin, oral midazolam, St. John's Wort or any ergot drugs. Kaletra may also complicate certain medical conditions. You may not be able to take Kaletra or may need to take special precautions if you have diabetes, high cholesterol or triglyceride levels, pancreas problems, a bleeding disorder, liver disease, a heart rhythm disorder, heart disease or a familial or individual history of long QT syndrome. You may also need to take different precautions if you have previously taken a different protease inhibitor. If you take Kaletra tablets while pregnant or breastfeeding, the drug may have a harmful effect on the fetus or your baby, so talk to your doctor about the risks. The drug can also lessen the effectiveness of pills or patches used for birth control. You are advised not to drink alcoholic beverages while taking this drug. Kaletra is only approved for infants over 14 days old or 14 days past the original due date for premature infants.  Kaletra will not cure HIV infection and will not prevent you from passing the infection to others through blood and other bodily fluids. You should discuss with your doctor ways to practice safe sex and to avoid passing on the infection while taking this drug.