What should I know about abacavir sulfate, lamivudine, and zidovudine?

You should know that you can still spread HIV while taking abacavir-lamivudine-zidovudine, the three antiretroviral medications found in the brand-name drug Trizivir. This medication does not cure HIV or AIDS. It can, however, slow the effects of the virus. You may still experience HIV- or AIDS-related problems. People with liver disease and people who weigh less than 90 pounds should not take this medication. You should also let your doctor know if you have heart problems, diabetes, blood pressure problems, high cholesterol or any other medical conditions. Hepatitis B may be worsened during this treatment. If you have the genetic variation HLA-B*5701, you are more at risk for serious complications. Some serious risks of taking abacavir-lamivudine-zidovudine tablets include: the development of lactic acidosis, allergic reactions, blood disorders, muscle disease and liver problems. Hypersensitivity is characterized by a serious multi-organ reaction to the medication, including two or more symptoms of fever, rash, gastrointestinal problems, general achiness or fatigue or respiratory problems. You should call your doctor if you develop any severe or persistent reactions. Some drugs can cause serious interactions with abacavir and lamivudine tablets. Tell your doctor if you are taking doxorubicin, emtricitabine, fluconazole, ganciclovir, interferon, methadone, phenytoin, ribavirin, stavudine, sulfamethoxazole, trimethoprim, SMZ-TMP or valproic acid. Do not smoke or drink alcohol while taking this medication. Tell your doctor if you are pregnant, planning to become pregnant or breastfeeding.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.