Can Edurant interact with other medications or foods?

Edurant (rilpivirine) can interact with other medications and supplements, increasing the risk of side effects or affecting how well the drugs work.

Before taking Edurant, a drug prescribed to treat human immunodeficiency virus type 1 (HIV-1), make a list of all medications (prescription and nonprescription) and supplements that you take and go over it carefully with your doctor. You may need to stop taking certain drugs or supplements before you start taking Edurant. Once you're taking Edurant, do not add any drugs or supplements to your routine without checking with your doctor first.

Following are a few substances that should not be taken with Edurant:
  • the supplement St. John's wort
  • anti-seizure medications including carbamazepine, phenobarbital, phenytoin and oxcarbazepine
  • anti-tuberculosis medicines rifabutin, rifampin and rifapentine
  • proton pump inhibitors including esomeprazole, lansoprazole, omeprazole, pantoprazole sodium and rabeprazole
  • more than one dose of the corticosteroid medicine dexamethasone or dexamethasone sodium phosphate.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.