How does lorazepam interact with other drugs or foods?

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Lorazepam can interact with certain drugs and foods.

You should not drink alcohol or use anesthetics, antidepressant medications, barbiturates and antipsychotics with lorazepam, as they can increase your risk of dangerous side effects, including drowsiness, memory loss, confusion and difficulty breathing. For the same reasons, be sure not to mix lorazepam with sleep or seizure medications, other benzodiazepines, divalproex, probenecid, narcotics or opiates.

The following drugs can also interact with lorazepam: probenecid, divalproex, ziprasidone, quetiapine, fluphenazine, clozapine, chlorpromazine, olanzapine, thioridazine, risperidone, trifluoperazine, aripiprazole, secobarbital, amobarbital, butalbital, phenobarbital, pentobarbital, clorazepate, chlordiazepoxide, diazepam, clonazepam, alprazolam, flurazepam, estazolam, midazolam, temazepam, triazolam, antihistamines, digoxin, levodopa, rifampin, an oral contraceptive, theophylline or valproic acid.

Before taking lorazepam, tell your doctor about all prescription and over-the-counter drugs you are taking, as well as any vitamins and supplements. Also, tell your doctor if you smoke, as smoking and tobacco use can make lorazepam less effective.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.