Should I take hydrocortisone pills with food?

You should take hydrocortisone pills (Cortef) with food or right after meals. By taking this prescription medicine with food, you will lessen the chance of getting an upset stomach. You should also take your medicine relatively early in the day to keep it from interfering with sleep. If you have any questions or concerns about taking hydrocortisone, talk with your doctor, healthcare provider or pharmacist.

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