Who should not use EMLA?

EMLA should not be used by anyone with a known allergy to its active ingredients, lidocaine and prilocaine or to any inactive ingredient including carboxypolymethylene. It should not be used by anyone allergic to similar medications, including novocaine, benzocaine, lidocaine, marcaine or tetracaine. EMLA should be used with caution in people with severe liver disease. EMLA can increase the risk of developing methemoglobinemia, especially in the very young or people known to be predisposed to methemoglobinemia. The disease occurs when too much of the blood temporarily is altered into a form that cannot carry oxygen. EMLA should be avoided in people who are known to have this condition or in people known to have a genetic deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD), a rare condition that can lead to a certain type of anemia and can also increase the risk of methemoglobinemia. EMLA should be used carefully by people on medicines that increase the risk of methemoglobinemia, such as Tylenol, acetanilide, para-aminosalicylic acid, Dilantin, phenobarbital, naphthalene, pamaquine, quinine, dapsone, nitroglycerin, nitroprusside, nitrofurantoin and other nitrates or nitrites. EMLA should be used carefully in patients who are seriously ill or debilitated, in patients of very advanced age and in infants, as these people might absorb more of the medicine through their skin and have more systemic side effects.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.