Who should not receive desflurane?

Desflurane should not be used on people with certain medical conditions. If you have familial periodic paralysis, muscular dystrophy, myasthenia gravis or Eaton-Lambert syndrome, you should talk to your doctor before having desflurane administered. Additionally, people who have had other conditions and diseases that cause muscle weakness should not take desflurane. If you have cardiac or vascular diseases, you should not have desflurane as an anesthetic as it increases your risk of certain side effects. If you've had liver problems after receiving desflurance or similar anesthetics, you should not receive it. Additionally, if you have malignant hyperthermia as a result of having had anesthesia, you should not have desflurane. You may experience a high fever, irregular or rapid heart rate, muscle spasms, tightness or breathing difficulties as a result.