What are the side effects of bupavacaine HCI and epinephrine injections?

Bupivacaine-epinephrine injection may cause temporary swelling or puffiness in the injection area for as long as seven hours. During this time, it is possible to injure yourself by chewing solid foods or testing the numb area by probing.
More serious side effects that require immediate medical attention include: depression, excitation, restlessness, anxiety, dizziness, ringing in the ears, blurry vision and tremors -- all signs of a central nervous system reaction. Serious cardiovascular reactions, such as cardiac arrest and irregular heartbeat, are also possible. Because this solution contains epinepherine, a vasoconstrictor, another side effect is contraction of blood vessels. For this reason, people with conditions, such as hypertension (high blood pressure), heart disease or diabetes, should be especially cautious when receiving a bupivacaine-epinephrine injection. Finally, neurological effects such as weakness or prolonged anesthesia (numbness) are possible.

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