What are the side effects of articaine and epinephrine injections?

Injections of articaine and epinephrine can cause the blood disorder methemoglobinemia. Symptoms include fatigue and blue nails and lips. Other potentially serious side effects include breathing problems, weakened heart rate, facial swelling, lightheadedness, swollen or bleeding gums, anxiety, blurry vision, tinnitus, and seizure. Less serious side effects include oral sores, thirst, nausea, nervousness, dizziness, various forms of pain, a strange taste, numbness, rash, runny nose, and sore throat. Accidental intravascular injection significantly increases the possibility of serious side effects.

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