Who should not take Xodol?

You shouldn't use the prescription pain medication Xodol (hydrocodone and acetaminophen) if you have had an allergic reaction to acetaminophen, hydrocodone or other narcotic or opioid drug.

Xodol may not be recommended for the following people:
  • pregnant women
  • women who are breastfeeding
  • children
  • people with liver or kidney disease
  • people with underactive thyroid glands
  • people who have Addison's disease
  • men with enlarged prostate glands
  • people who have narrowing of the urethra
  • people with lung disease 
  • people who take certain other medications, including antidepressants, antihistamines, antianxiety or antipsychotic medications or other narcotic drugs. Before taking Xodol, give your doctor and pharmacist a list of all your other medicines (prescription and nonprescription) and dietary and herbal supplements. (People who take Xodol should not take any new medicines without consulting their doctor or pharmacist first.)
  • people who drink alcohol and will not stop while taking Xodol
In addition, some people should be particularly cautious when they start Xodol:
  • People who have to drive or operate machinery should see how Xodol affects them before attempting these activities.
  • People ages 65 and older may need to be started on a very low dose of Xodol.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.