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Who should not take Ultracet?

You should not take the prescription pain medication Ultracet (tramadol and acetaminophen) if you:
  • have liver disease
  • suffer from alcoholism
  • are allergic to tramadol, acetaminophen or any other ingredient in this medication or any other opioid drug
You should not take Ultracet without talking with your doctor if you use any other drug that depresses the central nervous system, such as alcohol, opioids, narcotics, tranquilizers or sedative hypnotics, or if you drink alcohol. Your doctor may not prescribe Ultracet, or may prescribe it with caution, if you're taking any of a number of drugs, including:
  • an antidepressant called a selective serotonin reuptake inhibitor, or SSRI (such as Zoloft and Prozac)
  • an antidepressant called a monoamine oxidase inhibitor, or MAOI (such as Nardil and Parnate)
  • lithium
  • St. John's wort
Before you take Ultracet, give your doctor a complete medical history. Tell him or her about all your other medications (prescription or over-the-counter) as well as any supplements that you take.