Who should not take Tylenol with Codeine?

You should not take Tylenol with Codeine (acetaminophen and codeine) if you are allergic to any of its ingredients—especially codeine, acetaminophen or sulfite. You may not be able to take this prescription pain reliever if you are elderly or debilitated or if you have or have had one or more of the following medical problems:
  • liver or kidney problems
  • head injuries or any other condition that caused high pressure within your skull
  • acute abdominal conditions
  • hypothyroidism (underactive thyroid)
  • a urinary problem called urethral stricture (a narrowing of the urethra)
  • Addison’s disease (a disorder of your adrenal gland)
  • in men, an enlarged prostate
  • a history of alcoholism

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.