When should I call my doctor if I am taking Synalgos-DC?

If you are taking Synalgos-DC (dihydrocodeine, aspirin, caffeine), a prescription medication for moderate to severe pain, you should call your doctor if you experience certain side effects that could be serious or fatal. In particular, you or someone who is with you should seek emergency medical attention if you have any symptoms of an overdose such as these:
  • difficult, shallow or slowed breathing
  • extreme drowsiness or restlessness
  • blue lips
  • constricted pupils
  • fainting/unconsciousness
  • seizures
  • heartbeat that's too slow or fast
You should also call your doctor right away if you have any symptoms of a severe allergic reaction such as:
  • hives
  • difficulty breathing
  • swelling of the face, lips, tongue or throat
In addition, you should call your doctor if you have black, bloody, or tarry stools or are coughing up blood or vomit that looks like coffee grounds.

Also, call your doctor immediately if you have any of these side effects:
  • muscle twitching or pounding heartbeat
  • confusion, unusual thoughts or behavior
Call your doctor if any of these serious side effects persist or become troublesome:
  • lightheadedness, dizziness, shakiness, anxiety or agitation
  • drowsiness, sedation
  • mild nausea, vomiting, constipation or heartburn
  • dry mouth, sweating or urinating more than usual
  • ringing in ears
  • skin reactions, including itching or rash

You should call your doctor right away if you become pregnant while taking Synalgos-DC.

If you want or need to take a new medicine or supplement while taking Synalgos-DC, talk with your doctor first. Certain medications and supplements may interact with this drug and cause serious side effects.

If you want to stop taking Synalgos-DC, call your doctor. Stopping the drug suddenly may cause withdrawal symptoms.

You should call your doctor if your dose of Synalgos-DC is not helping relieve your moderate to moderately severe pain, or you find you have to take more than eight doses (two capsules per dose) a day. Your doctor may need to adjust your dose of Synalgos-DC or your other pain medicine.

Continue Learning about Analgesic

What should I avoid while taking analgesics?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
Until you know how you will react to analgesics, you should not drive or operate any heavy machinery...
More Answers
What are the risks of using opioid analgesics to treat pain?
Diana MeeksDiana Meeks
Opioid analgesics, such as morphine and codeine, are the primary treatment for acute pain. A person ...
More Answers
What type of narcotics or opioid analgesics will I be given after surgery?
Stuart A. Linder, MDStuart A. Linder, MD
Most commonly in my practice is the use of a combination of acetaminophen and codeine. Vicodin is us...
More Answers
How do analgesics interact with other medications?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
If you are taking certain medications, you should talk to your doctor before taking an analgesic. Th...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.