What are the possible side effects of Synalgos-DC?

Synalgos-DC (dihydrocodeine, aspirin, caffeine), a prescription drug used to treat moderate to severe pain, can cause side effects. The most common include:
  • lightheadedness, dizziness, shakiness, anxiety or agitation
  • drowsiness, sedation
  • mild nausea, vomiting, constipation
  • dry mouth, sweating or urinating more than usual
  • ringing in ears
  • skin reactions or itching
If any of these symptoms are severe or won't go away, tell your doctor. Call your doctor immediately if you experience any of these rarer but more serious symptoms:
  • shallow breathing and slow heart rate
  • fast or pounding heart rate
  • muscle twitching
  • confusion, unusual thoughts or behavior
  • black, bloody or tarry stools
  • coughing up blood or vomit that looks like coffee grounds

Synalgos-DC may cause physical dependence. Do not stop taking the drug, or any other opioid, without talking to your doctor first. Suddenly stopping Synalgos-DC may cause withdrawal symptoms.

There is a risk of abuse or addiction with this medication. The chance is increased if you are, or have ever been, addicted to or abused other medicines, street drugs or alcohol, or if you have a history of mental health problems.

Synalgos-DC can cause severe respiratory depression or even death in children following surgery to remove tonsils or adenoids. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.