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What should I know about Percodan before taking it?

Before taking Percodan, you should know that it is a combination of two pain relievers, oxycodone and aspirin, that is prescribed to treat moderate to severe pain. Percodan may make you drowsy. Do not drive or do any other activity that demands mental alertness before you know how Percodan affects you.

You also should know that this medicine may cause dizziness or lightheadedness when you stand up. Take care to get up slowly.

Do not drink alcohol while taking Percodan. Mixing alcohol with Percodan is dangerous.

You should know that certain medical conditions and habits can increase the risk of side effects from Percodan. Before you start taking it, inform your doctor if you have a history of any of the following:
  • hemophilia or other bleeding disorders
  • constipation or other intestinal problems
  • drinking more than three alcoholic drinks per day
  • drug abuse or addiction
  • a respiratory disease, such as asthma
  • a head injury
  • ulcers
  • reaction to aspirin, oxycodone or other medicines, foods, dyes or preservatives
It's important to know that oxycodone, a component of Percodan, can be habit-forming. Do not take a larger dose, take it more frequently or take it for a longer period of time than directed. Keep Percodan out of the sight and reach of children, in a place where it cannot be stolen.

As your body becomes used to this medicine, you may need a higher dose for pain relief, but do not change your dose on your own -- talk to your doctor. Do not stop taking oxycodone suddenly or you may experience symptoms of withdrawal.

Percodan may cause side effects. If you have any of the following symptoms, call your doctor immediately:
  • a rash or hives, swelling of your face, lips or tongue, eyes, hands, feet, lower legs or ankles or trouble breathing (these are signs of an allergic reaction that requires emergency medical help)
  • black-colored bowel movements
  • changes in your eyesight
  • chest pain
  • difficulty with or changes in urination
  • fatigue
  • trouble swallowing
  • hoarseness
  • fainting or loss of consciousness
  • hallucinating
  • fast heartbeat
  • mental confusion
  • fever, chills, aches and pains
  • light-headedness
  • seizures
  • bleeding or bruising
Side effects that do not typically require treatment unless they are severe or don't go away include:
  • constipation
  • dizziness
  • drowsiness
  • dry mouth
  • headache
  • nausea
  • vomiting
  • sweating
  • depression
  • itching
  • loss of appetite

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.