What are possible side effects of Xodol?

The most common side effects of Xodol (hydrocodone and acetaminophen), a drug prescribed to relieve moderate to moderately severe pain, include light-headedness, dizziness, sedation, nausea and vomiting. Sometimes simply lying down can relieve these symptoms, but you should call your doctor if any symptom is severe or persistent. Other side effects may include:
  • sleepiness and/or lethargy
  • mental health symptoms such as cloudy thinking, anxiety, fear, feeling uneasy or unwell
  • constipation
  • trouble urinating or urinating completely
  • skin rash or itching
  • blood test abnormalities -- low platelet or white blood cell count
Serious side effects are more likely to occur if you take too much Xodol. Take Xodol exactly as prescribed by your doctor -- do not take more than recommended, even if the drug becomes less effective at relieving your symptoms. Excessive doses of Xodol can cause dangerously slowed breathing and heartbeat, flaccid muscles, cold and/or clammy skin, stupor, coma, serious liver damage, kidney damage and even heart attack and death. If you think you have accidentally taken too much Xodol, tell your doctor immediately -- do not wait until you develop symptoms.