What should I know about Magnacet before taking it?

Before you start taking the pain medication Magnacet (oxycodone and acetaminophen), you should know that it contains two drugs, acetaminophen and the narcotic oxycodone. It's possible to become addicted to this medication, especially if you have a history of addiction. Let your doctor know if you've ever had this problem.

You should know that Magnacet can cause serious side effects and that you shouldn't take more of it, or use it more often, than recommended. Many medications interact with Magnacet, so you should tell your doctor about any other drugs (prescription and nonprescription) and dietary supplements you use.

Make sure you're not taking another medication containing acetaminophen (which is widely used) or another narcotic painkiller (such as codeine, oxymorphone or morphine) without your doctor's knowledge. Very serious side effects can occur if you take too much of these drugs, including severe liver injury. The Food and Drug Administration recommends no more than 4,000 milligrams (mg) of acetaminophen a day. To prevent an unintentional overdose, it is recommended that you take no more than one acetaminophen-containing product a day.

You should avoid alcohol while taking Magnacet. Drinking can increase Magnacet's potency, raising the risk of dangerous side effects. It also further increases the risk of liver damage.

You should not take Magnacet if:
  • you're allergic to oxycodone, acetaminophen or any other ingredient in Magnacet
  • you have a respiratory problem, such as acute or severe bronchial asthma. Because Magnacet lowers your breathing rate, it can interfere with your ability to breathe if you have one of these conditions.
  • you have -- or might have -- a condition called paralytic ileus, a bowel obstruction that prevents digested food from passing through the intestines. Magnacet can worsen this condition.
  • you're pregnant or breastfeeding. If you take Magnacet, your baby may be born dependent on the drug and experience severe withdrawal symptoms. Magnacet passes into your breast milk and can interfere with your baby's breathing.
You should know that Magnacet can cause serious side effects if you have certain medical conditions. Give your doctor a complete medical history before you start the drug.
Finally, because Magnacet can make you drowsy, do not drive or operate heavy machinery until you're certain you can remain alert while on it. Be extra cautious when you start the medication and anytime your dose is increased.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.