Can Ultracet interact with food or other medications?

The prescription pain medication Ultracet (tramadol and acetaminophen) can interact with a number of other drugs. Taking Ultracet with other drugs that depress the central nervous system, such as narcotics, tranquilizers and sedative hypnotics, can increase the risk of respiratory depression, in which breathing can become dangerously slow and shallow. If you're on Ultracet, you should be cautious about using these drugs. (For the same reason, you should not drink alcohol while you're on Ultracet.)

Ultracet also can interact with medications for depression, migraines, seizures, fungal infections and some heart conditions, as well as the herbal medication St. John's wort. Some of these drugs can increase your blood level of tramadol, raising the risk of serious side effects; others can reduce tramadol's effect, which can interfere with pain relief.

Before you start taking Ultracet, tell your doctor about all your other medications (prescription or over-the-counter) as well as any supplements you take. While you're taking Ultracet, do not start any other drug or supplement without first talking to your doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.