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What should I avoid while taking Tylenol with Codeine?

While you're taking Tylenol with Codeine (acetaminophen and codeine), you should avoid driving or operating machinery until you know how it affects you because this prescription pain reliever can affect your mental and physical abilities. You should avoid drinking alcohol or taking other central nervous system depressants, such as tranquilizers or sedatives, while you're on Tylenol with Codeine. In combination, they can increase your risk for serious side effects, including drowsiness, slowed breathing and loss of consciousness.

You should also avoid taking too much acetaminophen while you're on this drug because excessive amounts may cause liver damage. The Food and Drug Administration (FDA) recommends taking no more than 4,000 milligrams (mg) of acetaminophen a day. Keep in mind that many over-the-counter cold and flu medicines contain acetaminophen, as do assorted other remedies—read labels. It's best to avoid taking anything else that contains acetaminophen while you're on Tylenol with Codeine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.