What are the side effects of oxycodone and acetaminophen?

An allergic reaction to oxycodone and acetaminophen may cause swelling of your face, lips, tongue and throat, making it difficult to breathe. You may notice a rash or hives as well. Call 911 to get emergency medical help if you experience these symptoms.
Possible side effects of taking oxycodone and acetaminophen range from minor to serious. Call your doctor if you experience:

  • fainting or lightheadedness
  • confusion
  • seizure
  • unusual thoughts or actions
  • nausea with stomach pain and pale stools
  • dark urine with jaundice
  • shallow breathing
  • slow heartbeat

Other side effects include:

  • drowsiness
  • feeling relaxed and calm
  • sleepiness
  • belching
  • mood swings
  • constipation
  • fear or nervousness
  • indigestion
  • dry mouth

Call your doctor if these side effects become severe or won't go away.

An overdose can occur with this medication if you take too much of it. Call your doctor immediately if you or someone else has symptoms of overdose, such as decreased consciousness or unconsciousness, cold and clammy skin, extreme drowsiness, general discomfort or feeling of illness, slow or irregular heartbeat, lightheadedness, dizziness or fainting.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.