How does Midrin interact with other medications?

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Acetaminophen, isometheptene and dichloralphenazone (Midrin) can cause harm to your liver if combined with alcohol, so it is very important to avoid alcohol while taking this medication. Also, combining this medication with others that contain acetaminophen can be harmful. Check carefully to make sure any over-the-counter medicines, including cold medicines and other pain relievers, do not contain acetaminophen.

Monoamine oxidase inhibitors (MAOIs), such as phenelzine, should not be combined with this medication, so make sure you do not take this medication within two weeks of taking an MAOI. Also, acetaminophen, isometheptene and dichloralphenazone can cause excessive drowsiness when combined with antihistamines, antidepressants, muscle relaxants, sedatives and other medications that cause you to feel drowsy. In addition, your doctor needs to know all the other medications, vitamins and herbal supplements you take, to make sure these do not produce harmful side effects when combined with acetaminophen, isometheptene and dichloralphenazone.