Is it safe for my friend to drink a few glasses of wine while on Demerol?

Your friend should not drink wine or any other alcoholic beverages while taking Demerol. Demerol (also known as meperidine) can cause side effects, including sleepiness, dizziness, drowsiness and lightheadedness. Alcohol can increase these side effects. Your friend should also avoid taking any medicines or eating foods that contain alcohol while taking this medicine.